G-protein coupled receptors and autoantibodies

Affina Academy (Eds.)
2003, 58 pages
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The pathophysiological role of autoantibodies directed to G-protein coupled receptors and therapeutic strategies of antibody removal
G. Wallukat, E. Nissen, J. Müller, R. Brinckmann, I. Schimke, R. Kunze

Abstracts from short lectures

Autoantibodies against the beta1-adrenoceptor increase L-type Ca2+ current in human atrial myocytes
T. Christ, D. Dobrev, E. Wettwer, D. Müller D., M. Knaut, G. Wallukat, U. Ravens

Translocation of the transcription factor NF-kappa-B from cytoplasm into nucleus in cultured cells induced by TNF-alpha, and autoantibodies against alpha1-adrenergic, and AT1 receptor
W. Schulze, V. Homuth, E. Nissen, D. Neichel, P. S. Leung, G. Wallukat

Functional monoclonal antibodies against the human beta1-adrenergic receptor
R. Mobini , A. Staudt, G. Wallukat, A. Mijares, J. Hoebeke

Induction of beta1-adrenergic receptor-directed autoimmune cardiomyopathy in the rat
R. Jahns, V. Boivin, S. Triebel, L. Hein, G. Ertl, C. E. Angermann, M. J. Lohse

The occurrence of autoantibodies against G-protein coupled receptors is associated with oxidative stress
I. Schimke

Specific removal of autoantibodies against beta1-adrenergic receptor from patients with dilated cardiomyopathy: Results from a pilot study
J. Müller

Agonistic antibodies targeting angiotensin II type 1 receptor cause acute vascular rejection in the absence of immunological risk
D. Dragun, G. Wallukat, R. Dechend, J. H. Bräsen, D. N. Müller, H.-H. Neumayer, K. Budde, F. C. Luft

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