K. Conrad, M. Bachmann, W. Lehmann, U. Sack (Eds.)
Methods, Possibilities and Perspectives of Pre-symptomatic Tumor Diagnostics
INTRODUCTION
- H.-H. König: Economic aspects of pre-symptomatic tumor diagnostics
- P. Oehr: Perspectives of molecular diagnostics – From “omics“ to molecular imaging
Chapter 1: TUMOR AND AUTOIMMUNITY
- J.-Y. Zhang, E. K.L. Chan: Tumor specific autoimmune responses - Why and when do they develop?
- K. Conrad, D. Roggenbuck, M. Bachmann: Autoantibodies as indicators of tumor development
- M. Koslowski, Ö. Türeci, U. Sahin: Identification of tumor-associated autoantibodies by SEREX technology
- M. Montenarh: p53 autoantibodies in the diagnosis and prognosis of tumors
- K. Großmann, U. Wagner, S. Milius, K. Conrad, U. Canzler, M. Bachmann, W. Lehmann: The microblot – a new tool for multiparameter immunodiagnostics
Chapter 2: BIOMARKER AND PROTEOMIC ANALYSES
- R. Lamerz, P. Stieber: Tumor markers – Diagnostic relevance and perspectives
- B. Seliger: Identification of diagnostic biomarkers for tumors by proteome analysis
- S. Klein-Scory, W. Schmiegel, I. Schwarte-Waldhoff: Immunosecretomics: Identification of tumor associated antigens by serological screening of tumor cell secretomes
- J. Lichey: Overview and perspectives for the SELDI technology in early cancer diagnosis
- T. Elssner, M. Kostrzewa: CLINPROT – a MALDI-TOF MS based system for biomarker discovery and analysis
- A. Wiesner: ProteinChip® technology – Chances and perspectives in tumor diagnostics
- S. Holdenrieder: Circulating apoptotic markers in the diagnosis and prognosis of malignant tumors
- K. Schnurr, V. Muravsky, G. Seibt, G. Matthes: The analysis of functional characteristics of serum albumin – a novel possibility of early cancer diagnosis
Chapter 3: GENETIC ANALYSES AND DISSEMINATED TUMOR CELLS
- B. Jandrig: Identification and analysis of hereditary cancer susceptibility
- C. Pilarsky, R. Grützmann: The use of microarray based gene expression profiling for the diagnosis of malignancies
- M. Fleischhacker, B. Schmidt: Circulating nucleic acids – do they have a meaning in cancer research?
- A. Meye: Disseminated tumor cells in blood and bone marrow in patients with urologic tumors – Methods of detection and relevance
- U. Anderer: Human tumor cells in vivo & in vitro: Modulation of differentiation and behaviour - Influence on in vitro cytotoxicity testing?
Chapter 4: IMAGING TECHNOLOGIES AND ENDOSCOPICAL METHODS
- M. Hentschel, F. Müller, I. Brink: Potentials and limits of combined anatomical and functional imaging modalities in tumor diagnosis
- F. Stanzel: Autofluorescence bronchoscopy in early detection of central premalignant and malignant bronchial changes
- M. Hocke, E. Schulze, P. Gottschalk, C. F. Dietrich: The use of contrast enhanced endoscopic ultrasound in discrimination between focal pancreatitis and pancreatic cancer
- C. Krafft, W. Steller, R. Salzer: Infrared spectroscopic imaging - an analytical tool for tumor diagnostics
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